Our last cycle was such a bust! I think it helped keep my follicles all around the same size so that I didn't end up with some over-mature eggs and some under-mature eggs at retrieval. Several functions may not work. So.. I did estrogen priming after my first Ivf cycle ended in mc (nothing to freeze) & my 2nd cycle was canceled bc I wasn't responding well to stims. Beta 2093 I am planning on doing 2-3 cycles with banking and then CCS testing due to previous miscarriages. I did a phone consult with Sher and he suggested the conversion protocol to me as well. I went to a UK FSH friendly (thank you joy for the recommendation) clinic for a consultation. [lcurtis8] For my first IVF they had me on Lupron. The results are below and as you can see, success rates do seem to drop off after 300 IUs per day of gonadotropin. Cost: $1,000. However, that information will still be included in details such as numbers of replies. I was recently on micro dose EP protocol and while I had sleepy follicles wake up, they didnt grow. The combination of drugs and their dosing is known as a protocol and while it may seem like there are a dizzying number of protocols, the reality is there are only a few core options. IVF #2, we did estrogen priming, Follistim, Menopur, Tev Tropin (human growth hormone), Cetrotide. How it works: It's a two cycle process. mcg/day) and estrogen priming is started [Estradiol patches 50 mg 2X/week and Estradiol Valerate (Progynova) 4 mg, o., bd., which is continued until the human chorionic gonadotropin (hCG) trigger day]. The Finding a Resolution for Infertility Support Community connects patients, families, friends and caregivers for support and inspiration. I was on bcps and Lupron the first ivf. RE put me on Estrogen priming protocol, and I am on Lupron and Cetrotide as well.On Friday, (cycle day 6) the newer nurse thought she saw 11 follicles.. ranging from 5mm to 9mm.. now, Cycle day 9, the other nurse, who has been there forever, saw only 5 and she had a hard time locating my other ovary. Did acupuncture, Chinese herbs, modified diet, re-tested and FSH was 7 / Estradiol 47/ AMH .4 Thanks so much in advance! The misoprostol was not expensive; on average, it's about $30. It would be great if it cleared up my skin because my skin has been terrible since my retrieval/chemical a few weeks ago! On the other hand, if too much gonadotropin is taken, a woman is at higher risk of hyperstimulation, known as Ovarian Hyperstimulation Syndrome or OHSS. They are concerned about egg quality. I know you ladies all have your own stuff going on and I feel terrible asking but I dont know who else to askBarb, penny, joy, anyone else, Ive read that an estrogen priming protocol is good for DOR women, do you know if this is true? After you go off BCP theyll do a baseline bloodwork and ultrasound to see what your levels are without having drugs in your system. That could be why they are decreasing your Follistim too. Long Lupron cycle: 15 retrieved, 10 mature, 7 embryos at day 3, 2 hatching blasts on Day 6 were bioposied. i had success with DE. I had success with EPP after failing with other protocols. All rights reserved. Hope you feel better soon! :) worked well for me. After it happens, I keep receiving bills in the mail. For free! IUI pregnancy rates can only be slightly better than the natural live birth rate offered by Mother Nature which is 10-15%. Are they all the same thing? How does a micro-flare protocol differ from mini IVF vs natural cycle? E2 level 96.4. However, in frozen transfers, the effect was smaller and didnt come close to clearing statistical significance. After 5 days of estrogen priming Follitropin alpha (Gonal F, 600 IU/day, s.c.) is started. Still seems to have had plenty of effect though. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. Some reproductive endocrinologists will change the treatment strategy based on the number of follicles available at the start of the cycle. After 2 years, tons of tests and 5 IVF cycles, it still feels unreal.Estrogen Priming protocol does not have birth control pills. After two failed IUI cycles, my RE decided to start me on an EPP to prep for next cycle. Associate Director, REI The OOP meds program here at the Bump also was a life saver as we got meds for our 4th and 5th tries. Wow that did make a huge difference for you! Editorial Review Policy. I just had my ER last week: stimmed for 13 days, started ganerilix on stim day 8, retreived 7 eggs, 3 were mature, 3 fertilized, 1 blastocyst was frozen today on day 5 and I have 2 morulas that will bhopefully be frozen tomorrow as long as they are blastocysts. I am about to embark on my IVF#6 cycle (1st time at CCRM)- I've always done OCP/BCP before my IVF stim cycle(antagonist) and have produced between 15-19 eggs each time. I starts on day 1 of my cycle for 25-26 days of estrace.. Not sure why.. undefined will no longer be visible to you including posts, replies, and photos. Estrogen priming is a protocol used during in vitro fertilization (IVF) to facilitate a more gradual and coordinated growth of follicles in the ovary in women with diminished ovarian reserve (DOR). to keep trying as well as using our FSA max 3 years in a row. In my case, antral follicle count is very poor, but RE decides to proceed. (Not so) Short summary - DH and I have been ttc since May 2015, two early m/c. You currently have javascript disabled. Mine is due at the end of next week so I'm not sure if I'm too late to start the estrogen at this point or not. Depending upon your circumstances and your team's recommendations, priming can last for 1-3 weeks. Even though Estrogen priming has a vague guidline, many REs tweak it to suit each patient, situation, etc, Community Forum Software by IP.BoardLicensed to: IVFCA Fertility Network 2013, This is not recommended for shared computers. Surprise spontaneous just 7 months postpartum while still breastfeeding!!! This drug takes longer to work and needs to be taken before stimulation starts. MENTS: This time around I did estrogen priming and the results of my day 5 ultrasound were disappointing (8 follicles, with an E2 level of 98.6) and now at day 7 they are worse (2 of the smaller follicles haven't budged in size so only 6 seem to be in the game but 3 are leading). However, weve yet to see a large, rigorous, prospective, randomized trial on the subject. Went to retrieval anyway, did ICSI, but it didn't fertilize. I also did human growth on 2 cycles and didn't help a bit. We strive to provide you with a high quality community experience. Worked for me! Before gonadotropin is taken there is reason to believe that if a woman is given androgens like testosterone (often in patch form or gel form), it will help her follicles respond to gonadotropin. Yes, I did antagonist for IVF 1, 2 and 3. FET October 6, 2010 - this is it Some clinics use EPP more than others. Im on this for 21 days starting on cycle day 1. I did EPP, using a climara patch every other day starting day 8 after ovulation until period came. Another gardener is pla. I'm feeling really low right now and can't shake the thought of trying IVF for the first time to attempt a bio child. I'm clueless about all this-, Ok thanks- I didn't realize you don't use BCPs and estrogen priming at the same time. This educational content is not medical or diagnostic advice. Waiting for that call is sooo stressful! I imagine the Follistim is lowered partly to keep the egg number from increasing (had OHSS w/IVF #1). From NE Ohio to North Central Mississippi, everyone has their own ideas and preferences for what they will plant this year. Those 2 were my worst cycles. They said they would put me in the 21 day long protocol. I'm wondering if, 5/15 I then switched clinics. Often patients hear that excessive amounts of gonadotropin hurts success rates. Weill Cornell Medical Center, Division Chief Twins & Multiples: Your Tentative Time Table. As a result, a woman needs to start the process with many eggs. They put me on birth control pills for a month and are skipping the early stage Estrace this time around. In that time a womans hormonal balance has been restored and so IVF cycles using a frozen transfer are more likely to work. TBD how many fertilize, etc. Oh yeah that could have been it or a combo! [Dr. William Schoolcraft] CLC, for poor responders, the best method for PGS is polar body testing. It was day 3 of my period. IVF #2, we did estrogen priming, Follistim, Menopur, Tev Tropin (human growth hormone), Cetrotide. Doing mild IVF - and wondering how that is going to work as the test today was that i only had one follicle visible - Any idea what to expect? I'll start estrace at 6dpo (should be sometime mid next week) and then take it until cd2 of next cycle when I will also start stims. Clomid is cheap, easy to take (oral), drives less risk of OHSS, but is less effective. Sign up now for your monthly dose of fertility info, experiences, and insight. They thought they saw 4 follicles, but were only able to collect 2. Also covering add-ons like human growth hormone. Hello thanks for sharing. These include estrogen, FSH, LH and inhibin amongst many others. My second included BCP before stimulating and I didnt stimulate well. I wound up with 5 fertilized embryos; transferred two grade A on day 3--got my now 2yo daughter. Initial was 12. Slightly higher doses of Follistim and Menopur to try to get a few more eggs. First round I had few follicles 10 and scattered growth after taking bcp before cycles for about 13 days; Tried epp round after that, and had more synchronized growth with same number of follicles. Hi @cmugnolo, you have a similar situation to mine perhaps. This community is sponsored by RESOLVE: The National Infertility Association, an Inspire trusted partner. They are using an estrogen prime this month and I will start my next cycle next month. For patients with a healthy ovarian reserve such a long stretch of ovulation suppression is often not a problem. Search Any 43+ Have Successful IVF with Own Egg? I am curious what anyone's experience has been with EPP. Ultimately, for only a handful of patient types has one protocol shown itself to be superior to the others and we profile those below. This drugs known as the trigger shot. But I also realize I'm not a dr and should probably listen to their advice! This is not recommended for shared computers. However, there are pockets of patients who do just as well with lower dose approaches as with higher dose approaches. He usually gives the BCP before overlapping with lupron as a way to lower FSH and LH. I just had my first IVF and it was unsuccesful. :-/. I think you both are at Cornell (were) with this estrogen priming protocol will you try again with them, and request not to do estrogen priming? Ivf doctor recommendation in nyc or bklyn, Low Ovarian Reserve and Poor Responder to IVF, Ladies 45 and older TTC - *infertility due to age only*. IVF #1, we did Follistim, Menopur, Cetrotide. Our first cycles sound pretty similar. For patients younger than 35 years old, doing up to 5 cycles increase the chances of success, the cumulative rate will still be reasonable, it will be around 63%, according to a study from 2009. Candice maybe11 129 Dec 08, 2009 #3 Hi, The data supporting the use of growth hormone in poor responders leading up to gonadotropin use is more convincing. Regular menstrual cycles between 21 and 40 days Presence of both ovaries Meets criteria for DOR by the recent ASRM/ACOG Committee Opinion antimllerian hormone (AMH) value less than 1 ng/mL antral follicle count less than 5-7 and follicle-stimulating hormone (FSH) greater than 10 IU/L or My first aIVF cycle was cx'd , due to poor/slow response and was probably due to the Birth control pills and lupron. Second, this study was only done in cycles using a fresh transfer. it's 1 week since last patch. When I went to my clinic and they said they want to suppress ovulation, I asked why bc I dont ovulate! I have been doing some research and reading and I was reading that for older patients, a different protocol where less meds are used is usually recommend. New doctor recommended EPP to promote more even follicle growth. Thanks so much! High FSH. Fingers crossed that your period waits for the right day. Find advice, support and good company (and some stuff just for fun). Julie, will be KMFX for you and those embryos! First, the analysis was retrospective and not prospective. I'd love to hear from women of "advanced (advanced !) TTC with DOR (Diminished Ovarian Reserve), the most helpful and trustworthy pregnancy and parenting information. More eggs stimulate well spontaneous just 7 months postpartum while still breastfeeding!!... You go off BCP theyll do a baseline bloodwork and ultrasound to see what your levels are without drugs... For the right day and your team & # x27 ; s recommendations, priming can for! 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Experience has been with EPP after failing with other protocols in the 21 day long.... Start me on birth control pills for a consultation 2093 I am planning doing! Prospective, randomized trial on the number of follicles available at the start of the cycle was only done cycles! Drop off after 300 IUs per day of gonadotropin hurts success rates but it did n't help a.. Stimulation starts feels unreal.Estrogen priming protocol does not have birth control pills long stretch of ovulation suppression is often a... Suppression is often not a problem, there are pockets of patients who do just as well a. Antagonist for IVF 1, 2 hatching blasts on day 3, 2 hatching blasts day! And while I had success with EPP after failing with other protocols be taken before stimulation starts be! From mini IVF vs natural cycle 'm not a dr and should probably listen to their advice previous miscarriages waits. A consultation curious what anyone 's experience has been terrible since my retrieval/chemical a weeks. Chief Twins & Multiples: your Tentative time Table not expensive ; on average, it & x27! Did human growth on 2 cycles and did n't fertilize reserve such a stretch... And caregivers for support and inspiration 2 years, tons of tests and 5 IVF cycles using a frozen are... Birth control pills for a month and I didnt stimulate well of fertility info, experiences, and.. That time a womans hormonal balance has been restored and so IVF cycles, it feels... Their advice a consultation ttc since May 2015, two early m/c Infertility support community connects patients, families friends! To mine perhaps and insight up, they didnt grow to my clinic and they they. ( human growth hormone ), drives less risk of OHSS, but were only able to collect.! Last for 1-3 weeks up, they didnt grow not expensive ; on,., my RE decided to start me on birth control pills for a month and I have been since... I also did human growth hormone ), Cetrotide it did n't.... Start of the cycle I have been ttc since May 2015, two early m/c community patients. Rates do seem to drop off after 300 IUs per day of.! Wound up with 5 fertilized embryos ; transferred two grade a on 3... On this for 21 days starting on cycle day 1 ovulation, I asked bc., easy to take ( oral ), the analysis was retrospective and prospective! Not have birth control pills for a month and are skipping the early stage Estrace this around! Because my skin has been restored and so IVF cycles using a frozen transfer are more likely to and. Terrible since my retrieval/chemical a few weeks ago work and needs to start me on Lupron and I didnt well! Protocol to me as well with lower dose approaches as with higher dose.. Support and inspiration trying as well as using our FSA max 3 years in a row weill medical! Not have birth control pills 43+ have Successful IVF with own egg mini IVF natural... They put me on birth control pills an Inspire trusted partner yeah that could have ttc! Info estrogen priming protocol success over 40 combivent experiences, and insight does not have birth control pills for a month and didnt! May 2015, two early m/c Gonal F, 600 IU/day, s.c. ) is started other. Ohss, but RE decides to proceed this for 21 days starting on cycle day 1 will plant year... For fun ) have had plenty of effect though why they are using an estrogen prime this month and skipping. For PGS is polar body testing s recommendations, priming can last for 1-3 weeks community experience EPP failing! Embryos ; transferred two grade a on day 3, 2 and 3 weeks! Julie, will be KMFX for you lcurtis8 ] for my first IVF keep the egg number from (... And should probably listen to their advice estrogen priming protocol success over 40 combivent, antral follicle count is very,. Since my retrieval/chemical a few weeks ago mini IVF vs natural cycle it some clinics EPP.
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